Mixed Adenoneuroendocrine Carcinoma in the Transverse Colon: An Infrequent Neoplasm in an Unusual Location

Mixed adenoneuroendocrine carcinoma of the colon: molecular pathogenesis and treatment.

BACKGROUND/AIM We report a case of a mixed adenoneuroendocrine carcinoma developed in a colorectal adenocarcinoma with lymph node and liver metastases exclusively emanating from the neuroendocrine carcinoma component. The patient underwent right hemicolectomy and postoperatively received chemotherapy with cisplatin and etoposide and subsequent high-dose induction chemotherapy, followed by autol...

An unusual foreign body in the transverse colon.

Perivascular epithelioid cell neoplasm of the uterine cervix: an unusual tumor in an unusual location

A 46-year-old woman presented for a second opinion regarding a 3-4 cm mass of the uterine cervix. A prior biopsy had been interpreted as a malignant melanoma of the cervix, resulting in a radical hysterectomy with bilateral salpingooophorectomy. This was to be followed by external beam irradiation and immunotherapy; however, given the rarity of this diagnosis, the patient sought a second opinio...

Gastric Mixed Adenoneuroendocrine Carcinoma

o t ( o i a j t n g t t d p s o t r t astrointestinal mixed adenoneuroendocrine carcinomas MANECs) are rare tumors and, as the name implies, are haracterized by the presence of both components, exocrine nd neuroendocrine, each one representing at least 30% of he lesion.1 It is unclear if they originate from proliferation f different cell lineages or from stem cells capable of differntiating alo...

Clinicopathological features of an ascending colon mixed adenoneuroendocrine carcinoma with clinical serosal invasion.

Mixed adenoneuroendocrine carcinoma (MANEC) is exceedingly rare with a poor outcome. In this article, we reported a MANEC in a 68-year-old woman with a symptom of abdominal pain and distension. MANEC derived from the ascending colon with highly aggressive behavior. The diagnosis and distinguish of MANEC must base on histological findings and immunohistochemical findings. In this case, microscop...